Some centuries later, the descendants of the first settlers were confronted by a new influence. The King and Queen defeated the rebellion and those who still refused to be cleansed fled from Earth to the desolate planet of Nemesis. Some people refused to be purified and they rebelled. Some time after Neo-Queen Serenity came into power, she initiated a cleansing of all of the people on Earth using the Silver Crystal. Once she became Queen, Serenity ceased to age. Through the power of the Silver Crystal the people of the Earth became functionally immortal. Some time after the twentieth century the Earth was struck by an ice age which froze in time the entire population for 1000 years, until it was saved by Usagi in the 30th Century, at which point she ascended to power as Neo-Queen Serenity. Also, Diana spoke of the future King and Queen both falling ill just before stuffy official ceremonies, and miraculously recovering as soon as they were over.

She also had a penchant for using smiley faces in her letters, as well as heading them with a cute drawing of herself. For example, she sent an unusually cute letter with Chibiusa to Usagi and Mamoru, which demonstrated the fact that even after several centuries she was still unable to write well in kanji. Neo-Queen Serenity was much more composed and regal than her younger self, but there were hints that she still retained some of her goofy traits. In both the anime and manga canon, Neo-Queen Serenity sent her child, Chibiusa, into the past to train to be a Sailor Senshi after the threat in the future ended. The details of her ascension to the throne and the subsequent attacks varied according to the source. She ascended the throne along with her husband, Endymion, and rules all of Earth from the Crystal Palace (situated in what was formerly the Juuban district) with the power of the Silver Crystal. Neo-Queen Serenity is the future form of Sailor Moon.

Axens neo queen serenity